This dual payload is delivered directly through dissolving MNs, which bypass ocular barriers enabling localized, sustained, and minimally invasive transscleral administration
Currently, various therapeutic approaches have been devised based on this treatment strategy, including treatment with a combination of Minoxidil and Spironolactone, as well as innovative approaches such as the use of platelet-rich plasma (PRP), stromal vascular fraction (SVF), and conditioned media, and stem cell therapies, as well as the use of mesenchymal stem cells (MSCs) due to their powerful paracrine properties and excellent immunomodulatory effects [15, 16]
Hypokalaemia is particularly concerning as it can cause dangerous cardiac arrhythmias
The authors reported dapagliflozin use was associated with a 3.0 kg weight loss as well as improvements in several other metabolic markers [64]
This controlled degradation allows space for new, healthy matrix deposition